Size :50ul
Clone Number:
Aliases:Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)], SPN, CD43
Product Type:Monoclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P16150
Immunogen:Synthesized peptide derived from human CD43
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response .
Clonality:Monoclonal
Isotype:IgG1, Kappa
Purification Method:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Conjugate:Non-conjugated
Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:SPN
Research Areas:Immunology