Size :50ug
Clone Number:4D1H11
Aliases:Parathyroid hormone, PTH
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P01270
Immunogen:Recombinant PTH Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA
Background:Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids, yet effective hormone-receptor interaction requires solely the 34-N-terminal amino acids. While PTH acts to increase the concentration of ionic calcium (Ca2+) in the blood, calcitonin, a hormone produced by the parafollicular cells (C cells) of the thyroid gland, acts to decrease ionic calcium concentration. PTH essentially acts to increase the concentration of calcium in the blood by acting upon the parathyroid hormone 1 receptor, which is present at high levels in bone and kidney, and the parathyroid hormone 2 receptor, which is present at high levels in the central nervous system, pancreas, testis, and placenta.PTH half-life is approximately 4 minutes. It has a molecular mass of approximately 9.4 kDa.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:>95%,Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PTH
Research Areas:Signal transduction