Size :50 Tests
Clone Number:
Aliases:
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P28906
Immunogen:Recombinant Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Background:D34 reacts with CD34 molecule, a 105-120 kDa heavily O-glycosylated transmembrane glycoprotein expressed on hematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting that CD34 may play a role in signal transduction. CD34 may play a role in adhesion of specific antigens to endothelium. Clone 43A1 belongs to the class II epitope. * CD34 mAb is useful for detection and saparation of hematopoietic stem cells.1. Schlossman, SL et al., eds. (1995) Leucocyte Typing V : White Cell Differentiation Antigens, Oxford University Press, New York.2. Freeman SD et al., (1995) Blood 85:20053. Thomas R and Lipsky PE. (1994) J Immunol 153:40164. Nakamura Y. et al., (1994) Blood 83:1442
Clonality:Monoclonal
Isotype:IgG3
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CD34
Research Areas:Neuroscience?Cancer?Cardiovascular;Developmental biology;Immunology;Stem cells