BMI1 Antibody - Cat. #: CSB-RA916472A0HU

BMI1 Antibody - Cat. #: CSB-RA916472A0HU

CSB-RA916472A0HU
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Size :50ul

Clone Number:1F2

Aliases:Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51), BMI1, PCGF4 RNF51

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35226

Immunogen:A synthesized peptide derived from human Bmi1

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200

Background:Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BMI1

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Stem cells

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