Size :50ul
Clone Number:7G3
Aliases:Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2), BACE1, BACE KIAA1149
Product Type:Recombinant Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P56817
Immunogen:A synthesized peptide derived from human BACE1
Raised in:
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000
Background:Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Clonality:Monoclonal
Isotype:Rabbit IgG
Purification Method:Affinity-chromatography
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:BACE1
Research Areas:Neuroscience; Cell biology