Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P51672
Uniprot Entry Name:XCL1_RAT
Gene Names:Xcl1,Ltn,Scyc1
Species:Rattus norvegicus (Rat)
Source:E.Coli
Expression Region:22-114aa
Sequence:VGTEVLQESI CVSLRTQRLP VQKIKTYTIK EGAMRAVIFV TKRGLRICAD PQAKWVKTAI KTVDGRASAS KSKAETIPTQ AQRSASTAVT LTG
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:10.0 kDa
Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100 ng/ml, corresponding to a specific activity of ? 1.0 ×104 IU/mg.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:C motif chemokine 1, Small-inducible cytokine C1
Relevance:Chemotactic activity for lymphocytes but not for monocytes or neutrophils. {ECO:0000250}.
PubMed ID:9717977
Function:Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine gamma family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=90962
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:171371
STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000003976
OMIM Database Link: