Recombinant Mouse Granulocyte colony-stimulating factor protein(Csf3) (Active)

Recombinant Mouse Granulocyte colony-stimulating factor protein(Csf3) (Active)

CSB-AP003161MO
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Size:100ug. Other sizes are also available. Please contact us.

Research Areas:Immunology

Uniprot NO.:P09920

Uniprot Entry Name:CSF3_MOUSE

Gene Names:Csf3,Csfg

Species:Mus musculus (Mouse)

Source:E.Coli

Expression Region:31-208aa

Sequence:VPLVTVSALP PSLPLPRSFL LKSLEQVRKI QASGSVLLEQ LCATYKLCHP EELVLLGHSL GIPKASLSGC SSQALQQTQC LSQLHSGLCL YQGLLQALSG ISPALAPTLD LLQLDVANFA TTIWQQMENL GVAPTVQPTQ SAMPAFTSAF QRRAGGVLAI SYLQGFLETA RLALHHLA

Protein Description:Full Length of Mature Protein

Tag Info:Tag-Free

Mol. Weight:18.9 kDa

Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NFS­60 cells is less than 0.05 ng/ml, corresponding to a specific activity of ? 2.0 × 107 IU/mg.

Purity:>98% as determined by SDS­PAGE and HPLC.

Endotoxin:Less than 1.0 EU/µg as determined by LAL method.

Form:Lyophilized powder

Buffer:Lyophilized from a 0.2 m filtered 10 mM Sodium Citrate, pH 4.0, 150 mM NaCl, 0.01 % Tween­20

Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Alternative Name/ Alias:G-CSF,

Relevance:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.

PubMed ID:3489940; 3494605; 3501294

Function:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.

Involvement in disease:

Subcellular Location:Secreted

Protein Families:IL-6 superfamily

Tissue Specificity:

Paythway:

HGNC Database Link:

UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=1238

KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:12985

STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000037762

OMIM Database Link:

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