Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Signal Transduction
Uniprot NO.:P12710
Uniprot Entry Name:FABPL_MOUSE
Gene Names:Fabp1,Fabpl
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:1-127aa
Sequence:MNFSGKYQLQ SQENFEPFMK AIGLPEDLIQ KGKDIKGVSE IVHEGKKIKL TITYGPKVVR NEFTLGEECE LETMTGEKVK AVVKLEGDNK MVTTFKGIKS VTELNGDTIT NTMTLGDIVY KRVSKRI
Protein Description:Full Length
Tag Info:Tag-Free
Mol. Weight:14.2 kDa
Biological_Activity:Fully biologically active when compared to standard. The binding affinity of rMuFABP1 for the synthetic ligand cis-parinaric acid has been measured by fluorescence titration. Half maximal fluorescence of 2.5 ?M rMuFABP1 is achieved with approximately 5 ?M cis-paranaric acid.
Purity:>95% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, 2 % trehalose.
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:14 kDa selenium-binding protein, Liver-type fatty acid-binding protein, L-FABP
Relevance:Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Also seems to bind selenium.
PubMed ID:15489334; 2760043; 21183079; 23806337; 23576753
Function:Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
Involvement in disease:
Subcellular Location:Cytoplasm
Protein Families:Calycin superfamily, Fatty-acid binding protein (FABP) family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=22126
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:14080
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000064655
OMIM Database Link: