Recombinant Mouse Fatty acid-binding protein, liver protein(Fabp1) (Active)

Recombinant Mouse Fatty acid-binding protein, liver protein(Fabp1) (Active)

CSB-AP000551MO
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Size:100ug. Other sizes are also available. Please contact us.

Research Areas:Signal Transduction

Uniprot NO.:P12710

Uniprot Entry Name:FABPL_MOUSE

Gene Names:Fabp1,Fabpl

Species:Mus musculus (Mouse)

Source:E.Coli

Expression Region:1-127aa

Sequence:MNFSGKYQLQ SQENFEPFMK AIGLPEDLIQ KGKDIKGVSE IVHEGKKIKL TITYGPKVVR NEFTLGEECE LETMTGEKVK AVVKLEGDNK MVTTFKGIKS VTELNGDTIT NTMTLGDIVY KRVSKRI

Protein Description:Full Length

Tag Info:Tag-Free

Mol. Weight:14.2 kDa

Biological_Activity:Fully biologically active when compared to standard. The binding affinity of rMuFABP1 for the synthetic ligand cis-parinaric acid has been measured by fluorescence titration. Half maximal fluorescence of 2.5 ?M rMuFABP1 is achieved with approximately 5 ?M cis-paranaric acid.

Purity:>95% as determined by SDS-PAGE and HPLC.

Endotoxin:Less than 1.0 EU/µg as determined by LAL method.

Form:Lyophilized powder

Buffer:Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4, 2 % trehalose.

Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Alternative Name/ Alias:14 kDa selenium-binding protein, Liver-type fatty acid-binding protein, L-FABP

Relevance:Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Also seems to bind selenium.

PubMed ID:15489334; 2760043; 21183079; 23806337; 23576753

Function:Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.

Involvement in disease:

Subcellular Location:Cytoplasm

Protein Families:Calycin superfamily, Fatty-acid binding protein (FABP) family

Tissue Specificity:

Paythway:

HGNC Database Link:

UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=22126

KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:14080

STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000064655

OMIM Database Link:

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