Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:Q60753
Uniprot Entry Name:CTF1_MOUSE
Gene Names:Ctf1
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:1-203aa
Sequence:MSQREGSLED HQTDSSISFL PHLEAKIRQT HNLARLLTKY AEQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSVLPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP GPEPVTVATL FTANSTAGIF SAKVLGFHVC GLYGEWVSRT EGDLGQLVPG GVA
Protein Description:Full Length
Tag Info:Tag-Free
Mol. Weight:21.5 kDa
Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF1 cells is less than 0.5 ng/ml, corresponding to a specific activity of ? 2.0 × 106 IU/mg.
Purity:>95% as determined by SDSPAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:CT-1,
Relevance:Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
PubMed ID:7862649; 15489334
Function:Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:IL-6 superfamily
Tissue Specificity:Highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels in testis and brain. No expression in spleen.
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=389954
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:13019
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000049161
OMIM Database Link: