Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Neuroscience
Uniprot NO.:O60542
Uniprot Entry Name:PSPN_HUMAN
Gene Names:PSPN
Species:Homo sapiens (Human)
Source:E.Coli
Expression Region:61-156aa
Sequence:ALSGPCQLWS LTLSVAELGL GYASEEKVIF RYCAGSCPRG ARTQHGLALA RLQGQGRAHG GPCCRPTRYT DVAFLDDRHR WQRLPQLSAA ACGCGG
Protein Description:Partial
Tag Info:Tag-Free
Mol. Weight:10.3 kDa
Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TT medullary thyroid cancer cells is less than 10 ng/ml, corresponding to a specific activity of ? 1.0 × 105 IU/mg.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:PSP,
Relevance:Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.
PubMed ID:9491986
Function:Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:TGF-beta family, GDNF subfamily
Tissue Specificity:
Paythway:
HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:9579
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=248159
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:5623
STRING Database Link:https://string-db.org/network/9606.ENSP00000245810
OMIM Database Link:https://www.omim.org/entry/602921602921602921