Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P01562
Uniprot Entry Name:IFNA1_HUMAN
Gene Names:IFNA1;,IFNA13
Species:Homo sapiens (Human)
Source:E.Coli
Expression Region:24-189aa
Sequence:M+CDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMNVDSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM RSLSLSTNLQ ERLRRKE
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:19.5 kDa
Biological_Activity:Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 1.0 × 108 IU/mg.
Purity:>96% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4, containing 4 % mannitol and 1 % HSA
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:IFN-alpha-1/13, LeIF D
Relevance:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. {ECO:0000269|PubMed:1634550}.
PubMed ID:6157600; 6157095; 6163083; 6479148; 4057246; 2985969; 20857263; 15164053; 15489334; 6310510; 1634550; 9425112; 11032395; 22307521
Function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Alpha/beta interferon family
Tissue Specificity:
Paythway:
HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:5417
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=37026
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:3439
STRING Database Link:https://string-db.org/network/9606.ENSP00000276927
OMIM Database Link:https://www.omim.org/entry/147578147578147578