NUP153 Antibody - Cat. #: CSB-RA986790A0HU

SKU: CSB-RA986790A0HU

Size :50ul

Clone Number:8D4

Aliases:Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153), NUP153

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P49790

Immunogen:A synthesized peptide derived from human Nup153

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200

Background:Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NUP153

Research Areas:Epigenetics and Nuclear Signaling; Tags & Cell Markers; Signal transduction