
Size :50ul
Clone Number:
Aliases:CARD 4 antibody; CARD4 antibody; Caspase recruitment domain 4 antibody; Caspase recruitment domain containing protein 4 antibody; Caspase recruitment domain family member 4 antibody; Caspase recruitment domain protein 4 antibody; Caspase recruitment domain-containing protein 4 antibody; CLR 7.1 antibody; CLR7.1 antibody; NLR family CARD domain containing 1 antibody; NLRC 1 antibody; NLRC1 antibody; NOD 1 antibody; Nod1 antibody; NOD1 protein antibody; NOD1_HUMAN antibody; Nucleotide binding oligomerization domain containing 1 antibody; Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1 antibody; Nucleotide-binding oligomerization domain-containing protein 1 antibody; Protein Nod1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9Y239
Immunogen:Synthetic peptide of Human NOD1
Raised in:Rabbit
Species Reactivity:Human, Mouse
Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:50-1:200
Background:This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:NOD1
Research Areas:Cell biology
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