KISS1 Antibody - Cat. #: CSB-PA595662

CSB-PA595662

Size :50ul

Clone Number:

Aliases:KISS 1 antibody; KiSS 1 metastasis suppressor antibody; Kiss1 antibody; KISS1_HUMAN antibody; Kisspeptin 1 antibody; Kisspeptin 10 antibody; Kisspeptin 13 antibody; Kisspeptin 14 antibody; Kisspeptin antibody; Kisspeptin-1 antibody; Kisspeptin-10 antibody; Kisspeptin-54 antibody; Kisspeptin1 antibody; Malignant melanoma metastasis suppressor antibody; Metastasis suppressor KiSS 1 antibody; Metastasis suppressor KiSS1 antibody; Metastin antibody; MGC39258 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15726

Immunogen:Synthetic peptide of Human KISS1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:5-1:20

Background:This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KISS1

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Cell biology