Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Immunogen:histone deacetylase 3
Synonyms:HD3, RPD3, RPD3-2, HDAC3
Observed MW:49 kDa
Uniprot ID:O15379
Reactivity:Human
Tested Application:ELISA, IHC, WB
Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Gene ID:8841
Research Area:Epigenetics, Cardiovascular, Metabolism