
Size :50ul
Clone Number:
Aliases:20 lyase antibody; CP17A_HUMAN antibody; CPT7 antibody; CYP17 antibody; CYP17A1 antibody; CYPXVII antibody; Cytochrome P450 17A1 antibody; Cytochrome P450 family 17 antibody; Cytochrome P450 family 17 subfamily A polypeptide 1 antibody; Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia antibody; Cytochrome p450 XVIIA1 antibody; Cytochrome P450-C17 antibody; Cytochrome P450c17 antibody; OTTHUMP00000020382 antibody; P450 C17 antibody; P450c17 antibody; S17AH antibody; Steroid 17 alpha hydroxylase/17,20 lyase antibody; Steroid 17 alpha monooxygenase antibody; Steroid 17-alpha-hydroxylase/17 antibody; Steroid 17-alpha-monooxygenase antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P05093
Immunogen:Fusion protein of Human CYP17A1
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200
Background:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CYP17A1
Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction
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