Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Immunogen:beta-site APP-cleaving enzyme 1
Synonyms:BACE, KIAA1149
Observed MW:70-75 kDa
Uniprot ID:P56817
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IP, IHC
Recommended dilution:WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:100-1:400
Gene ID:23621
Research Area:Neuroscience, Metabolism