Size :50ug
Clone Number:
Aliases:Activin A receptor antibody; Activin A receptor type II like 1 antibody; Activin A receptor; type II like kinase 1 antibody; Activin receptor like kinase 1 antibody; Activin receptor-like kinase 1 antibody; ACVL1_HUMAN antibody; ACVRL1 antibody; ACVRLK1 antibody; ALK-1 antibody; ALK1 antibody; HHT antibody; HHT2 antibody; ORW2 antibody; Osler Rendu Weber syndrome 2 antibody; Serine/threonine protein kinase receptor R3 antibody; Serine/threonine-protein kinase receptor R3 antibody; SKR3 antibody; TGF B superfamily receptor type I antibody; TGF-B superfamily receptor type I antibody; TSR-I antibody; TSR1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P37023
Immunogen:Recombinant Human Serine/threonine-protein kinase receptor R3 protein (22-118AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200
Background:Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ACVRL1
Research Areas:Cancer; Cardiovascular; Metabolism; Signal transduction