Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:15824131).
Immunogen:Zwilch, kinetochore associated, homolog(Drosophila)
Synonyms:FLJ10036, FLJ16343, hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH
Observed MW:67 kDa
Uniprot ID:Q9H900
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:200-1:2000; IHC: 1:20-1:200
Gene ID:55055
Research Area:Cell Division and Proliferation