Size :100ul
Clone Number:
Aliases:CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P19320
Immunogen:Purified recombinant fragment of human VCAM1 expressed in E. Coli
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500
Background:This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity-chromatography
Conjugate:Non-conjugated
Buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:VCAM1
Research Areas:Neuroscience?Cancer?Cardiovascular;Signal transduction?Stem cells