Size :50ug
Clone Number:1A1B1
Aliases:S100B ,S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P04271
Immunogen:Recombinant Human S100B protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA
Background:Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:>95%,Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:S100B
Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Stem cells