Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P17559
Uniprot Entry Name:UTER_RAT
Gene Names:Scgb1a1,Cc10,Ugb,Utg
Species:Rattus norvegicus (Rat)
Source:E.Coli
Expression Region:20-96aa
Sequence:SSDICPGFLQ VLEALLLGSE SNYEAALKPF NPASDLQNAG TQLKRLVDTL PQETRINIVK LTEKILTSPL CEQDLRV
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:8.5 kDa
Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 ?g/ml, corresponding to a specific activity of ? 200 IU/m.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:Clara cell phospholipid-binding protein, Clara cells 10 kDa secretory protein, CC10, PCB-binding protein, Secretoglobin family 1A member 1
Relevance:Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
PubMed ID:2115524; 15489334; 2349092; 1560460; 7583672
Function:Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Secretoglobin family
Tissue Specificity:Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=2206
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:25575
STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000027342
OMIM Database Link: