Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P48973
Uniprot Entry Name:CXL10_RAT
Gene Names:Cxcl10,Inp10,Mob1,Scyb10
Species:Rattus norvegicus (Rat)
Source:E.Coli
Expression Region:22-98aa
Sequence:IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:8.7 kDa
Biological_Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR3 transfected HEK293 cells is in a concentration range of 10-50 ng/ml.
Purity:>95% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:10 kDa interferon gamma-induced protein, IP-10, Interferon-inducible protein 10, Protein Mob-1, Small-inducible cytokine B10
Relevance:In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development. {ECO:0000250}.
PubMed ID:8798675
Function:In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine alpha (chemokine CxC) family
Tissue Specificity:Spleen.
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=10584
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?rno:245920
STRING Database Link:https://string-db.org/network/10116.ENSRNOP00000003649
OMIM Database Link: