Size:20ug. Other sizes are also available. For further information, please contact us.
Research Areas:Cell Biology
Uniprot ID:P48038
Gene Names:ACR
Organism:Oryctolagus cuniculus (Rabbit)
AA Sequence:KDNATCDGPCGLRFRQNPQGGFRVVGGQAAQQGAWPWMVSLQIFTPRNNRRYHACGGVLLNAHWVLTAAHCFNNKQKVYEWRMVFGAQEIEYGTDKPVRPPLQERYVEKVVTHDQYNYMTEGNDIALLKITPPVPCGPFIGPGCLPNSKAGPPKAAQTCYVAGWGYVKENAPRPSPTLMEARVDLINLELCNSTQWYNGRITASNLCAGYPSGKIDTCQGDSGGPLMCRENQGEPFVVQGITSWGVGCARAKRPGIYTATWPFLDWIASRIGSNALRMIQPATPTPPTTRSPGVHQPPSAHPPWYFQHASGPPHPHPHPHPHPHPRPPQPPAAQAPPPPPPPPPPPPPPPPPPPPPPPPPPPASTKPPQALSFAKRLQQLVEVLKGGSTFSGAKRVDTAAAAAEATEIPEVTLAS
Expression Region:17-431aa
Sequence Info:Full Length of Mature Protein
Source:Yeast
Tag Info:N-terminal 6xHis-tagged
MW:46.3 kDa
Alternative Name(s):
Relevance:Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
Reference:"Cloning and sequencing of cDNAs for rabbit preproacrosin and a novel preproacrosin-related cDNA." Richardson R.T., O'Rand M.G. Biochim. Biophys. Acta 1219:215-218(1994)
Purity:Greater than 90% as determined by SDS-PAGE.
Form:Liquid or Lyophilized powder
Buffer:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function:
Involvement in disease:
Subcellular Location:
Protein Families:
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:
KEGG Database Link:
STRING Database Link:
OMIM Database Link:
Lead Time Guidance:25-35 business days