Size:100ug. Other sizes are also available. For further information, please contact us.
Research Areas:Cardiovascular
Uniprot ID:P97295
Gene Names:Npy2r
Organism:Mus musculus (Mouse)
AA Sequence:MGPVGAEADENQTVEVKVEPYGPGHTTPRGELPPDPEPELIDSTKLVEVQV
Expression Region:1-51aa
Sequence Info:Extracellular Domain
Source:E.coli
Tag Info:N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
MW:25.5 kDa
Alternative Name(s):NPY-Y2 receptor (Y2 receptor)
Relevance:Receptor for neuropeptide Y and peptide YY.
Reference:"Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor." Naveilhan P., Hassani H., Canals J.M., Ekstrand A.J., Larefalk A., Chhajlani V., Arenas E., Gedda K., Svensson L., Thoren P., Ernfors P. Nat. Med. 5:1188-1193(1999)
Purity:Greater than 85% as determined by SDS-PAGE.
Form:Liquid or Lyophilized powder
Buffer:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function:Receptor for neuropeptide Y and peptide YY.
Involvement in disease:
Subcellular Location:Cell membrane, Multi-pass membrane protein
Protein Families:G-protein coupled receptor 1 family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=1433
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:18167
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000096595
OMIM Database Link:
Lead Time Guidance:13-23 business days