Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P04401
Uniprot Entry Name:IL5_MOUSE
Gene Names:Il5,Il-5
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:21-133aa
Sequence:MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:13.1 kDa
Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of ? 5.0 × 105 IU/mg.
Purity:>98% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 m filtered 20 mM Tris, pH 9.0, 150 mM NaCl
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:IL-5, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor
Relevance:Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
PubMed ID:3133208; 3024009; 3078564; 2215480
Function:Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:IL-5 family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=4461
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:16191
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000043369
OMIM Database Link: