Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:Q9JJY9
Uniprot Entry Name:IL22_MOUSE
Gene Names:Il22,Il22a,Iltif,Iltifa
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:34-179aa
Sequence:LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:16.6 kDa
Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.2 ng/ml, corresponding to a specific activity of ? 5.0 × 106 IU/mg.
Purity:>96% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:IL-22, IL-TIF, IL-TIF alpha, Interleukin-22a, IL-22a
Relevance:Cytokine that contributes to the inflammatory response in vivo.
PubMed ID:10657629; 11197690; 15489334
Function:Cytokine that contributes to the inflammatory response in vivo.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:IL-10 family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=103585
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:50929
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000094449
OMIM Database Link: