Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:Q9WUQ5
Uniprot Entry Name:CXL14_MOUSE
Gene Names:Cxcl14,Bmac,Kec,Ks1,Mip2g,Scyb14
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:23-99aa
Sequence:SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIVTTKS MSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:9.4 kDa
Biological_Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.
Purity:>95% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:B-cell and monocyte-activating chemokine, Kidney-expressed chemokine CXC, MIP-2G, Small-inducible cytokine B14,
Relevance:Chemotactic for CESS B-cells and THP-1 monocytes, but not T-cells. {ECO:0000269|PubMed:10784614}.
PubMed ID:10049774; 10784614; 10946286; 16141072; 15489334;
Function:Chemotactic for CESS B-cells and THP-1 monocytes, but not T-cells.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine alpha (chemokine CxC) family
Tissue Specificity:Highly expressed in brain, lung, ovary, muscle and in kidney and liver parenchyma, and at lower levels in bone marrow.
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=30211
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:57266
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000021970
OMIM Database Link: