Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P17515
Uniprot Entry Name:CXL10_MOUSE
Gene Names:Cxcl10,Crg2,Ifi10,Inp10,Scyb10
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:22-98aa
Sequence:IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:8.7 kDa
Biological_Activity:Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 0.1- 10.0 ng/ml in the presence of IL-2.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:10 kDa interferon gamma-induced protein, IP-10, C7, Interferon-gamma induced protein CRG-2, Small-inducible cytokine B10
Relevance:In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.
PubMed ID:2189406; 2118520; 8454640; 15489334; 8145049; 18560148
Function:In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine alpha (chemokine CxC) family
Tissue Specificity:Expressed in the spleen, thymus, lymph nodes and liver.
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=877
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:15945
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000047646
OMIM Database Link: