Recombinant Mouse C-C motif chemokine 9 protein(Ccl9) (Active)

Recombinant Mouse C-C motif chemokine 9 protein(Ccl9) (Active)

CSB-AP001281MO
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Size:100ug. Other sizes are also available. Please contact us.

Research Areas:Immunology

Uniprot NO.:P51670

Uniprot Entry Name:CCL9_MOUSE

Gene Names:Ccl9,Mrp2,Scya10,Scya9

Species:Mus musculus (Mouse)

Source:E.Coli

Expression Region:22-122aa

Sequence:QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q

Protein Description:Full Length of Mature Protein

Tag Info:Tag-Free

Mol. Weight:11.6 kDa

Biological_Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 0.1-10 ng/ml.

Purity:>95% as determined by SDS-PAGE and HPLC.

Endotoxin:Less than 1.0 EU/µg as determined by LAL method.

Form:Lyophilized powder

Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Alternative Name/ Alias:CCF18, MIP-1-gamma, Macrophage inflammatory protein-related protein 2, MRP-2, Small-inducible cytokine A9

Relevance:Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.

PubMed ID:8597875; 7650394; 7594550; 10438970; 19468303; 15905581

Function:Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.

Involvement in disease:

Subcellular Location:Secreted

Protein Families:Intercrine beta (chemokine CC) family

Tissue Specificity:Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.

Paythway:

HGNC Database Link:

UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=416125

KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:20308

STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000019266

OMIM Database Link:

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