Recombinant Mouse C-C motif chemokine 8 protein(Ccl8) (Active)

Recombinant Mouse C-C motif chemokine 8 protein(Ccl8) (Active)

CSB-AP001271MO
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Size:100ug. Other sizes are also available. Please contact us.

Research Areas:Immunology

Uniprot NO.:Q9Z121

Uniprot Entry Name:CCL8_MOUSE

Gene Names:Ccl8,Mcp2,Scya8

Species:Mus musculus (Mouse)

Source:E.Coli

Expression Region:24-97aa

Sequence:GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP

Protein Description:Full Length of Mature Protein

Tag Info:Tag-Free

Mol. Weight:8.5 kDa

Biological_Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100 ng/ml.

Purity:>97% as determined by SDS-PAGE and HPLC.

Endotoxin:Less than 1.0 EU/µg as determined by LAL method.

Form:Lyophilized powder

Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Alternative Name/ Alias:Monocyte chemoattractant protein 2, MCP-2, Small-inducible cytokine A8

Relevance:Chemotactic factor that attracts monocytes. This protein can bind heparin (By similarity). {ECO:0000250}.

PubMed ID:16141072

Function:Chemotactic factor that attracts monocytes. This protein can bind heparin (By similarity).

Involvement in disease:

Subcellular Location:Secreted

Protein Families:Intercrine beta (chemokine CC) family

Tissue Specificity:

Paythway:

HGNC Database Link:

UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=42029

KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:20307

STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000009329

OMIM Database Link:

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