Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P27784
Uniprot Entry Name:CCL6_MOUSE
Gene Names:Ccl6,C10,Scya6
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:22-116aa
Sequence:GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:10.7 kDa
Biological_Activity:Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a concentration range of 10-100 ng/ml.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:Protein C10, ,; CCL623-95,],
Relevance:CCL6(22-95) and CCL6(23-95) are potent chemoattractants. {ECO:0000269|PubMed:15905581}.
PubMed ID:1832565; 10438970; 16141072; 19468303; 15489334; 15905581
Function:CCL6(22-95) and CCL6(23-95) are potent chemoattractants.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine beta (chemokine CC) family
Tissue Specificity:Expressed in myelopoietic bone marrow cultures stimulated by GM-CSF.
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=137
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:20305
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000019071
OMIM Database Link: