Size:100ug. Other sizes are also available. For further information, please contact us.
Research Areas:Others
Uniprot ID:A2I7N1
Gene Names:SERPINA3-5
Organism:Bos taurus (Bovine)
AA Sequence:LPENVVVKDQRRRVDSHTLASSNTDFAFSLYKQLALKNPNKNVMFSPLSVSMALAFLSLGARGPTLTEILEGLKFNLTEIQETQIHQGFQHLLQALNRPSNQLQLSVGNAMFVQEELKLLDKFIEDARVLYSSEAFPTNFRDSEAARSLINDYVKNKTQGKIEELFKYLSPRTVLVLVNYIYFKAQWKTRFDPKHTEQAEFHVSKNKTVEVPMMTLDLETPYFRDKELGCMLVELTYSSNDSALFILPDEGKMQDLEAKLTPETLTRWRNSLQPRRIHELYLPKFSIKSNYELNDTLSQMGIKKIFTDADLSGITGTADLVVSQVVHGAALDVDEEGTEGAAATGIGIERTFLRIIVRVNRPFLIAVVLKDTQSIIFLGKVTNPSEA
Expression Region:25-411aa
Sequence Info:Full Length of Mature Protein
Source:Yeast
Tag Info:N-terminal 10xHis-tagged and C-terminal Myc-tagged
MW:47.8 kDa
Alternative Name(s):SERPINA3-5; Serpin A3-5
Relevance:Serine protease inhibitor.
Reference:"An original SERPINA3 gene cluster: elucidation of genomic organization and gene expression in the Bos taurus 21q24 region." Pelissier P., Delourme D., Germot A., Blanchet X., Becila S., Maftah A., Leveziel H., Ouali A., Bremaud L. BMC Genomics 9:151-151(2008)
Purity:Greater than 90% as determined by SDS-PAGE.
Form:Liquid or Lyophilized powder
Buffer:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function:Serine protease inhibitor.
Involvement in disease:
Subcellular Location:Cytoplasmic vesicle, secretory vesicle, chromaffin granule, Secreted
Protein Families:Serpin family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Bt&CID=55387
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?bta:617667
STRING Database Link:https://string-db.org/network/9913.ENSBTAP00000009264
OMIM Database Link:
Lead Time Guidance:25-35 business days