
Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 . CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).
Immunogen:ORAI calcium release-activated calcium modulator 1
Synonyms:CRACM1, FLJ14466, ORAI1, ORAI1 L1, ORAI1 L2, Orail L2, ORAT1, Protein orai 1, TMEM142A, Transmembrane protein 142A
Observed MW:45 kDa
Uniprot ID:Q96D31
Reactivity:Human, Mouse, Rat, Zebrafish
Tested Application:ELISA, WB, IF
Recommended dilution:WB: 1:500-1:1000; IF: 1:10-1:100
Gene ID:84876
Research Area:Immunology, Signal Transduction