
Size :50ul
Clone Number:
Aliases:A/G specific adenine DNA glycosylase antibody; A/G-specific adenine DNA glycosylase antibody; Adenine DNA glycosylase antibody; CYP2C antibody; hMYH antibody; MGC4416 antibody; MutY (E. coli) homolog antibody; MutY homolog (E. coli) antibody; MutY homolog antibody; MutY, E. coli, homolog of antibody; Mutyh antibody; MUTYH_HUMAN antibody; MYH antibody; rMYH antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9UIF7
Immunogen:Fusion protein of Human MUTYH
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200
Background:This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:MUTYH
Research Areas:Epigenetics and Nuclear Signaling