ISL1 Antibody - Cat. #: CSB-RA941933A0HU

SKU: CSB-RA941933A0HU

Size :50ul

Clone Number:1A1

Aliases:Insulin gene enhancer protein ISL-1 (Islet-1), ISL1

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P61371

Immunogen:A synthesized peptide derived from human Islet1

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200

Background:DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ISL1

Research Areas:Neuroscience; Cardiovascular; Developmental biology; Stem cells