Size :50ul
Clone Number:2C7
Aliases:DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1) (Inhibitor of differentiation 1), ID1, BHLHB24 ID
Product Type:Recombinant Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P41134
Immunogen:A synthesized peptide derived from human Id1
Raised in:
Species Reactivity:Human, Mouse
Tested Applications:ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200
Background:Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity).
Clonality:Monoclonal
Isotype:Rabbit IgG
Purification Method:Affinity-chromatography
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ID1
Research Areas:Epigenetics and Nuclear Signaling; Cancer; Signal transduction