Size :100ul
Clone Number:
Aliases:CSNB1B antibody; DKFZp686H1993 antibody; GluR6 antibody; Glutamate receptor metabotropic 6 antibody; GPRC1F antibody; Grm6 antibody; GRM6_HUMAN antibody; Metabotropic glutamate receptor 6 antibody; mGlu6 antibody; mGluR6 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:O15303
Immunogen:Synthesized peptide derived from Human GluR6.
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100
Background:G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.
Inga Everts, J. Neurosci., Feb 1999; 19: 916.
Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 - 40173.
Sheng Yan, J. Neurosci., Jan 2004; 24: 679.
Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 - 17445.
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GRM6
Research Areas:Neuroscience;Signal transduction