Size :50ul
Clone Number:
Aliases:Endoglin (CD antigen CD105), ENG, END
Product Type:Monoclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P17813
Immunogen:Synthesized peptide derived from human CD105(Endoglin)
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
Clonality:Monoclonal
Isotype:IgG2b, Kappa
Purification Method:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Conjugate:Non-conjugated
Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ENG
Research Areas:Immunology