Size :50ul
Clone Number:9H2D3
Aliases:Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3], CDH1, CDHE UVO
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P12830
Immunogen:Recombinant Human Cadherin-1 protein (155-707AA)
Raised in:Mouse
Species Reactivity:Human, Mouse
Tested Applications:ELISA, WB, IF, FC; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200
Background:Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:>95%, Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CDH1
Research Areas:Cancer; Developmental biology; Signal transduction