Size :100ul
Clone Number:
Aliases:
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P01732
Immunogen:Recombinant Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,FC
Background:COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development.1. Engleman EG et al. (1981) J Exp Med 153: 193-198.2. Haynes,B et al. (1986) Leukocyte TypingII: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Parnes, JR. et al. (1989). Adv. Immunol. 44,256-311.4. Bikah G. et al. (1996). Science 274:1906
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CD8A
Research Areas:Immunology