Size :100ul
Clone Number:
Aliases:
Product Type:Monoclonal Antibody
Immunogen Species:Mouse
UniProt ID:P01732
Immunogen:Recombinant Protein
Raised in:Rat
Species Reactivity:Mouse
Tested Applications:ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Background:The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality:Monoclonal
Isotype:IgG2b
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CD8A
Research Areas:Immunology