Size:100ug
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:8D5
Isotype:IgG1
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Immunogen:BMI1 polycomb ring finger oncogene
Synonyms:BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Observed MW:37 kDa
Uniprot ID:P35226
Reactivity:Human, Mouse
Tested Application:ELISA, WB, IHC, IF, IP
Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Gene ID:648
Research Area:Epigenetics, Metabolism, Cancer, Developmental biology, Stem Cells, Cell Division and Proliferation