Size :50ul
Clone Number:
Aliases:HIST1H2BB antibody; H2BFFHistone H2B type 1-B antibody; Histone H2B.1 antibody; Histone H2B.f antibody; H2B/f antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P33778
Immunogen:Peptide sequence around site of Acetyl-Lys (16) derived from Human Histone H2B type 1-B
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB, ICC, IF; Recommended dilution: WB:1:100-1:1000, ICC:1:20-1:200, IF:1:50-1:200
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HIST1H2BB
Research Areas:Epigenetics and Nuclear Signaling