Size :50ul
Clone Number:
Aliases:Abcg5 antibody; ABCG5_HUMAN antibody; ATP binding cassette sub family G (WHITE) member 5 (sterolin 1) antibody; ATP binding cassette sub family G member 5 antibody; ATP-binding cassette sub-family G member 5 antibody; ATP-binding cassette; sub-family G (WHITE); member 5 antibody; Sterolin 1 antibody; Sterolin-1 antibody; STSL antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9H222
Immunogen:Synthetic peptide of Human ABCG5
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100
Background:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ABCG5
Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction