Size :50ul
Clone Number:
Aliases:ABC transporter antibody; ABC15 antibody; ABCG 2 antibody; ABCG2 antibody; ABCG2_HUMAN antibody; ABCP antibody; ATP binding cassette sub family G (WHITE) member 2 antibody; ATP binding cassette transporter G2 antibody; ATP-binding cassette sub-family G member 2 antibody; BCRP antibody; BCRP1 antibody; BMDP antibody; Breast cancer resistance protein antibody; CD338 antibody; CDw338 antibody; CDw338 antigen antibody; EST157481 antibody; GOUT1 antibody; MGC102821 antibody; Mitoxantrone resistance associated protein antibody; Mitoxantrone resistance-associated protein antibody; MRX antibody; Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody; MXR antibody; MXR1 antibody; Placenta specific ATP binding cassette transporter antibody; Placenta specific MDR protein antibody; Placenta-specific ATP-binding cassette transporter antibody; UAQTL1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9UNQ0
Immunogen:Synthetic peptide of Human ABCG2
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200
Background:The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ABCG2
Research Areas:Cancer;Tags & Cell Markers;Metabolism;Signal transduction?Stem cells