Size :50ul
Clone Number:
Aliases:2' 5' oligoadenylate binding protein antibody; 2''-5''-oligoadenylate-binding protein antibody; 2'5' oligoadenylate binding protein antibody; ABC 38 antibody; ABC38 antibody; ABCE 1 antibody; ABCE1 antibody; ABCE1_HUMAN antibody; ATP binding cassette sub family E (OABP) member 1 antibody; ATP binding cassette sub family E member 1 antibody; ATP-binding cassette sub-family E member 1 antibody; HuHP 68 antibody; HuHP68 antibody; OABP antibody; Ribonuclease 4 inhibitor antibody; Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor antibody; Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor antibody; Ribonuclease L inhibitor antibody; RLI antibody; RNase L inhibitor antibody; RNASEL1 antibody; RNASELI antibody; RNS 4I antibody; RNS4I antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P61221
Immunogen:Recombinant Human ATP-binding cassette sub-family E member 1 protein (320-599AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200
Background:Antagonizes the binding of 2-5A (5\\\'-phosphorylated 2\\\',5\\\'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjugate:Non-conjugated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ABCE1
Research Areas:Cancer; Immunology; Metabolism; Signal transduction