TINF2 Antibody - Cat. #: CSB-RA997969A0HU

TINF2 Antibody - Cat. #: CSB-RA997969A0HU

CSB-RA997969A0HU
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Size :50ul

Clone Number:5G11

Aliases:TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2), TINF2, TIN2

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BSI4

Immunogen:A synthesized peptide derived from human Tin2

Raised in:

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background:Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TINF2

Research Areas:Epigenetics and Nuclear Signaling

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