Size :50ul
Clone Number:
Aliases:HMGA 2 antibody; BABL antibody; High mobility group (nonhistone chromosomal) protein isoform I C antibody; High mobility group (nonhistone chromosomal) protein isoform IC antibody; High Mobility Group AT hook 2 antibody; High Mobility Group AT hook protein 2 antibody; High mobility group AT-hook protein 2 antibody; High mobility group protein HMGI C antibody; High mobility group protein HMGI-C antibody; High mobility group protein HMGIC antibody; High mobility group protein I, isoform C antibody; HMGA2 antibody; HMGA2_HUMAN antibody; HMGI C antibody; HMGIC antibody; LIPO antibody; Non histone chromosomal architectural protein HMGI C antibody; Non histone chromosomal architectural protein HMGIC antibody; Pygmy antibody; STQTL9 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P52926
Immunogen:Synthetic peptide of Human HMGA2
Raised in:Rabbit
Species Reactivity:Human, Mouse
Tested Applications:ELISA, WB; ELISA:1:1000-1:5000, WB:1:500-1:2000
Background:This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HMGA2
Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Developmental biology;Metabolism;Stem cells