Size :50ul
Clone Number:5E9
Aliases:Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X), BCL2L1, BCL2L BCLX
Product Type:Recombinant Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q07817
Immunogen:A synthesized peptide derived from human Bcl-XL
Raised in:
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
Background:Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Clonality:Monoclonal
Isotype:Rabbit IgG
Purification Method:Affinity-chromatography
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:BCL2L1
Research Areas:Cancer; Cell biology; Metabolism; Signal transduction